Synthesis and Antimicrobial Activity of Modified 1,3,4-Oxadiazoles and Their Sugar Derivatives

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Author

Chemistry Department, Faculty of Science, Menoufia University

Abstract

A number of new substituted [(nitro-1H-imidazol-1-yl)methyl]-1,3,4-oxadiazoles, their derived sugar hydrazones as well as their N- and S-substituted derivatives were synthesized and tested for their antimicrobial activity against Bscillus subtilis (Gram-positive), Pseudomonas aeruginosa (Gram-negative), and Streptomyces species (Actinomycetes). The synthesized compounds displayed different degrees of antimicrobial activities or inhibitory actions.

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